Cook Daniel L, Mejino Jose L V, Rosse Cornelius
Structural Informatics Group, University of Washington, Seattle, WA, USA.
Stud Health Technol Inform. 2004;107(Pt 1):336-40.
We describe the need for a Foundational Model of Physiology (FMP) as a reference ontology for "functional bioinformatics". The FMP is intended to support symbolic lookup, logical inference and mathematical analysis by integrating descriptive, qualitative and quantitative functional knowledge. The FMP will serve as a symbolic representation of biological functions initially pertaining to human physiology and ultimately extensible to other species. We describe the evolving architecture of the FMP, which is based on the ontological principles of the BioD biological description language and the Foundational Model of Anatomy (FMA).
我们阐述了构建生理学基础模型（FMP）作为“功能生物信息学”参考本体的必要性。FMP旨在通过整合描述性、定性和定量功能知识来支持符号查找、逻辑推理和数学分析。FMP将作为生物功能的符号表示，最初适用于人体生理学，最终可扩展到其他物种。我们描述了FMP不断发展的架构，它基于BioD生物描述语言和解剖学基础模型（FMA）的本体原则。
