Rosse Cornelius, Kumar Anand, Mejino Jose L V, Cook Daniel L, Detwiler Landon T, Smith Barry
Structural Informatics Group, Department of Biological Structure, University of Washington, USA.
AMIA Annu Symp Proc. 2005;2005:639-43.
The integration of biomedical terminologies is indispensable to the process of information integration. When terminologies are linked merely through the alignment of their leaf terms, however, differences in context and ontological structure are ignored. Making use of the SNAP and SPAN ontologies, we show how three reference domain ontologies can be integrated at a higher level, through what we shall call the OBR framework (for: Ontology of Biomedical Reality). OBR is designed to facilitate inference across the boundaries of domain ontologies in anatomy, physiology and pathology.
生物医学术语的整合对于信息整合过程不可或缺。然而,当术语仅通过其叶节点术语的对齐进行链接时,上下文和本体结构的差异就被忽略了。利用SNAP和SPAN本体,我们展示了如何通过我们所称的OBR框架(即生物医学现实本体)在更高层次上整合三个参考领域本体。OBR旨在促进跨解剖学、生理学和病理学领域本体边界的推理。