Suppr超能文献

局部复发性宫颈癌的手术切除:单机构70例患者系列研究。

Surgical resection of locally recurrent cervical cancer: a single institutional 70 patient series.

作者信息

Moutardier V, Houvenaeghel G, Martino M, Lelong B, Bardou V J, Resbeut M, Delpero J R

机构信息

Institut Paoli-Calmettes, and Université de la Méditerranée, 13273 Marseille, France.

出版信息

Int J Gynecol Cancer. 2004 Sep-Oct;14(5):846-51. doi: 10.1111/j.1048-891X.2004.14519.x.

Abstract

Pelvic recurrence of cervical cancer is a life-threatening situation and only local control can provide hope for remission. The aim of this study was to evaluate the role of surgery in the treatment of cervical cancer recurrence. This retrospective study analyzed a series of 70 patients who underwent resection of cervix locoregional recurrence. Thirteen patients had palliative salvage surgery for pelvic complications. Twenty-nine resections were considered as curative. Fifty recurrences required pelvic exenterations. The hospital mortality rate was 9% and the morbidity rate was 44%. Overall 5-year actuarial survival rate was 23%. Survival was significantly higher: (a) after curative resection and (b) after centropelvic recurrence resection. Local control was obtained in 48% of the cases and 13 patients are alive with a median follow-up of 75 months. In conclusion, the results of this small and heterogen series seem to justify an attempt to resection for centropelvic recurrences whenever possible. Palliative surgery should be reserved to salvage therapy and highly selected patients.

摘要

宫颈癌盆腔复发是一种危及生命的情况,只有局部控制才能带来缓解的希望。本研究的目的是评估手术在治疗宫颈癌复发中的作用。这项回顾性研究分析了一系列70例行宫颈局部区域复发切除术的患者。13例患者因盆腔并发症接受了姑息性挽救手术。29例切除被认为是根治性的。50例复发需要行盆腔脏器清除术。医院死亡率为9%,发病率为44%。总体5年精算生存率为23%。生存率显著更高:(a)根治性切除后;(b)盆腔中心复发切除后。48%的病例实现了局部控制,13例患者存活,中位随访时间为75个月。总之,这个小的异质性系列的结果似乎证明,只要有可能,就应尝试对盆腔中心复发进行切除术。姑息性手术应保留用于挽救治疗和经过严格挑选的患者。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验