Al-Riyami Bazdawi M, Al-Rawas Omar A, Hassan Mohammed O
Department of Medicine, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Sultanate of Oman.
Respirology. 2004 Aug;9(3):387-91. doi: 10.1111/j.1440-1843.2004.00608.x.
Normal lung function has been shown to be population specific. The aim of this study was to derive normal reference spirometric values for Omani children and adolescents.
Forced vital capacity (FVC), forced expiratory volume in 1 s (FEV(1)), peak expiratory flow and forced mid-expiratory flow were measured in 837 healthy Omani school children aged 6-19 years. Multiple linear regression analysis was performed for each spirometric parameter against age, height and weight for boys and girls separately.
All measured spirometric parameters increased with age and height and were significantly higher in boys than girls. Height explained the maximum variance for all parameters. After accounting for height in the prediction equations, the contribution of age and weight was minimal. The expiratory ratio (FEV(1)%FVC) was independent of age and height and its mean values (+/- standard deviation) were slightly higher in girls (91.1 +/- 6.1%) than boys (86.5 +/- 7.1%; P < 0.001). The predicted normal values of the subjects using the derived equations were between 5 and 10% lower than the respective values for subjects in Caucasian sample groups.
The developed prediction equations can be used in clinical practice in Oman and can be considered for use in neighbouring Arab countries.
已证明正常肺功能具有人群特异性。本研究的目的是得出阿曼儿童和青少年的正常肺量计参考值。
对837名6至19岁的健康阿曼学童测量了用力肺活量(FVC)、1秒用力呼气量(FEV₁)、呼气峰值流速和用力呼气中期流速。针对每个肺量计参数,分别对男孩和女孩的年龄、身高和体重进行多元线性回归分析。
所有测量的肺量计参数均随年龄和身高增加,且男孩显著高于女孩。身高解释了所有参数的最大方差。在预测方程中考虑身高后,年龄和体重的贡献最小。呼气比率(FEV₁%FVC)与年龄和身高无关,女孩的平均值(±标准差)略高于男孩(91.1±6.1%对86.5±7.1%;P<0.001)。使用推导方程得出的受试者预测正常值比高加索样本组受试者的相应值低5%至10%。
所制定的预测方程可用于阿曼的临床实践,并可考虑在邻近阿拉伯国家使用。