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心血管磁共振成像:当前及新兴应用

Cardiovascular magnetic resonance imaging: current and emerging applications.

作者信息

Lima João A C, Desai Milind Y

机构信息

Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.

出版信息

J Am Coll Cardiol. 2004 Sep 15;44(6):1164-71. doi: 10.1016/j.jacc.2004.06.033.

DOI:10.1016/j.jacc.2004.06.033
PMID:15364314
Abstract

Magnetic resonance (MR) imaging is gaining importance in cardiology as the newest, most complex, and rapidly emerging noninvasive test of choice for patients with a multitude of cardiovascular problems. It has long been recognized to provide an accurate and reliable means of assessing the function and anatomy of the heart and great vessels, but its emerging role as one of the dominant imaging modalities in other aspects of cardiology such as perfusion imaging, atherosclerosis imaging, and coronary artery imaging cannot be understated. As MR technology evolves, newer therapeutic applications are also being developed, including specific MR-compatible catheters for electrophysiology studies/ablation as well as interventional cardiology related procedures, which may alter the way we practice cardiology in the future. Also, MR is entering an important phase in its evolution, with an anticipated exponential growth in its current applications and through the development of newer molecular imaging applications. It is anticipated that such developments will be coupled to the utilization of molecular markers to index biologic processes to allow for their in vivo visualization. This combination of biochemical markers and imaging methodology will also usher in an era of molecular imaging during which much progress in the diagnosis and treatment of cardiovascular disease is anticipated.

摘要

磁共振(MR)成像在心脏病学领域正变得愈发重要,它是针对患有多种心血管问题的患者最新、最复杂且迅速兴起的无创首选检查方法。长期以来,人们一直认为它能提供评估心脏和大血管功能及解剖结构的准确且可靠的手段,但其在心脏病学其他方面(如灌注成像、动脉粥样硬化成像和冠状动脉成像)作为主要成像方式之一的新兴作用不容小觑。随着MR技术的发展,新的治疗应用也在不断开发,包括用于电生理研究/消融以及介入心脏病学相关手术的特定MR兼容导管,这可能会改变我们未来心脏病学的实践方式。此外,MR正进入其发展的一个重要阶段,预计其当前应用将呈指数增长,并通过开发更新的分子成像应用来实现。预计这些发展将与利用分子标记物来标记生物过程以实现其体内可视化相结合。生化标记物与成像方法的这种结合也将迎来一个分子成像时代,在此期间,预计心血管疾病的诊断和治疗将取得很大进展。

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