Rotenberg Brian W, Daniel Sam J, Nish Iain A, Ngan Bo Y, Forte Vito
Department of Otolaryngology, The Hospital for Sick Children, Elm Wing 6th Floor, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8.
Int J Pediatr Otorhinolaryngol. 2004 Oct;68(10):1251-6. doi: 10.1016/j.ijporl.2004.04.022.
A paucity of data exists in the literature regarding the pediatric bony myxoma. Controversy exists regarding both its histopathologic origins and surgical management. The purpose of this study was to report on our experience in managing these patients, including diagnostic work-up, histopathologic findings and an evaluation of surgical treatment outcomes.
A retrospective review was undertaken of all consecutive cases of pediatric bony myxoma treated between 1988 and 2001. Tumors were analyzed in terms of clinical data, imaging studies, histopathology and surgical treatment. A selective review of the literature regarding management of the bony myxoma is also presented.
Five lesions were identified, all of which occurred in the maxillary bone. Histopathologically our cases did not show a strong association with odontogenic epithelium. All cases were treated by surgical resection with conservative margins. No recurrences were documented over a mean follow-up period of 8.5 years.
The bony myxoma is a rare lesion in the pediatric population, and initial clinical or radiological misdiagnoses are not uncommon. The presupposed odontogenic origin of these tumors may need reassessment. Conservative resection with narrow margins is a safe and effective therapy for myxomas of the pediatric maxilla.
关于儿童骨黏液瘤的文献资料匮乏。其组织病理学起源和手术治疗均存在争议。本研究的目的是报告我们治疗这些患者的经验，包括诊断检查、组织病理学发现以及对手术治疗结果的评估。
对1988年至2001年间治疗的所有连续性儿童骨黏液瘤病例进行回顾性研究。从临床数据、影像学检查、组织病理学和手术治疗方面对肿瘤进行分析。还对关于骨黏液瘤治疗的文献进行了选择性回顾。
共识别出5个病灶，均发生在上颌骨。组织病理学检查显示，我们的病例与牙源性上皮无明显关联。所有病例均采用切缘保守的手术切除治疗。在平均8.5年的随访期内未记录到复发情况。
骨黏液瘤在儿童群体中是一种罕见病变，最初的临床或放射学误诊并不少见。这些肿瘤假定的牙源性起源可能需要重新评估。切缘狭窄的保守性切除是治疗儿童上颌骨黏液瘤的一种安全有效的方法。
