LaFleur Joanne, Oderda Gary M
Pharmacotherpay Outcomes Research Center, University of Utah, Salt Lake City, UT 84108, USA.
J Pain Palliat Care Pharmacother. 2004;18(3):81-7.
Successful pharmacotherapy requires patient compliance with the therapeutic regimen. The rate of non-compliance has been reported to be as low as 15% in some studies and the costs of non-compliance have been estimated to be between $396 and 792 million. Compliance, adherence, and persistence are defined. Subjective and objective methods used to measure compliance are reviewed. Subjective methods include patient self-reporting and physician estimates; these methods are generally inexpensive but have been shown to be unreliable. Objective methods include pill counting, electronic monitoring devices, and data reviews; these methods vary in cost and reliability.
成功的药物治疗需要患者遵守治疗方案。在一些研究中，不遵守治疗方案的比例据报道低至15%，不遵守治疗方案的成本估计在3.96亿美元至7.92亿美元之间。对依从性、坚持性和持续性进行了定义。对用于衡量依从性的主观和客观方法进行了综述。主观方法包括患者自我报告和医生评估；这些方法通常成本较低，但已被证明不可靠。客观方法包括药片计数、电子监测设备和数据审查；这些方法在成本和可靠性方面各不相同。
