Satyanarayana S, Sushruta K, Sarma G S, Srinivas N, Subba Raju G V
Pharmacology Division, Department of Pharmaceutical Services, Andhra University, Visakhapatnam, Andhra Pradesh 530-003, India.
J Herb Pharmacother. 2004;4(2):1-10.
The antioxidant activity of the aqueous extracts of five umbelliferous fruits--caraway (Carum carvi), coriander (Coriandrum sativum), cumin (Cuminum cyminum), dill (Anethum graveolens) and fennel (Foeniculum vulgare)--were investigated in comparison with the known antioxidant ascorbic acid in in vitro studies. The amount of aqueous extract of these five umbelliferous fruits and ascorbic acid needed for 50% scavenging of superoxide radicals was found to be 105 microg (caraway), 370 microg (coriander), 220 microg (cumin), 190 microg (dill), 205 microg (fennel) and 260 microg (ascorbic acid). The amount needed for 50% inhibition of lipid peroxide was 2100 microg (caraway), 4500 microg (coriander), 4300 microg (cumin), 3100 microg (dill), 4600 microg (fennel) and 5000 microg (ascorbic acid). The quantity needed for 50% inhibition of hydroxyl radicals was 1150 microg (caraway), 1250 microg (coriander), 470 microg (cumin), 575 microg (dill), 700 microg (fennel) and 4500 microg (ascorbic acid). The daily use of the above fruits in various forms is very common in India and the present study revealed strong antioxidant activity of their extracts that was superior to known antioxidant ascorbic acid and indicate their intake may be beneficial as food additives.
在体外研究中，对五种伞形科果实——葛缕子（Carum carvi）、芫荽（Coriandrum sativum）、孜然（Cuminum cyminum）、莳萝（Anethum graveolens）和茴香（Foeniculum vulgare）——水提取物的抗氧化活性与已知抗氧化剂抗坏血酸进行了比较。发现清除50%超氧阴离子自由基所需的这五种伞形科果实水提取物和抗坏血酸的量分别为105微克（葛缕子）、370微克（芫荽）、220微克（孜然）、190微克（莳萝）、205微克（茴香）和260微克（抗坏血酸）。抑制50%脂质过氧化物所需的量分别为2100微克（葛缕子）、4500微克（芫荽）、4300微克（孜然）、3100微克（莳萝）、4600微克（茴香）和5000微克（抗坏血酸）。抑制50%羟自由基所需的量分别为1150微克（葛缕子）、1250微克（芫荽）、470微克（孜然）、575微克（莳萝）、700微克（茴香）和4500微克（抗坏血酸）。在印度，上述果实以各种形式的日常食用非常普遍，本研究揭示了其提取物具有很强的抗氧化活性，优于已知抗氧化剂抗坏血酸，并表明摄入这些果实作为食品添加剂可能有益。
