Terzian C G, Simon P A
Section of General Internal Medicine, College of Medicine, University of Illinois, Chicago.
Ann Emerg Med. 1992 Mar;21(3):312-4. doi: 10.1016/s0196-0644(05)80895-9.
Asthmatic patients receive multiple drugs as part of their treatment program. When a subsequent allergic reaction occurs, the ethylenediamine component of aminophylline is usually not suspected as the etiologic agent. We present a case of ethylenediamine-induced delayed hypersensitivity reaction in a 46-year-old woman who received parenteral aminophylline for an acute asthma exacerbation. Patch testing for ethylenediamine was positive.