Whitehouse Richard W, Aslam Rizwan, Bukhari Marwan, Groves Clare, Cassar-Pullicino Victor
Department of Clinical Radiology, Manchester Royal Infirmary, Oxford Road, Manchester, M13 9WL, UK.
Skeletal Radiol. 2005 Apr;34(4):217-20. doi: 10.1007/s00256-004-0823-5. Epub 2004 Sep 8.
The sesamoid index was originally described as an aid to the diagnosis of acromegaly. We performed this study to assess the value of the thumb sesamoid index in the diagnosis of psoriatic arthropathy.
Retrospective measurement of the sesamoid index (length x width of the medial thumb sesamoid), along with the age and sex were recorded for patients as described below. Patients with psoriasis were subdivided into those with or without radiographic evidence of hand arthropathy.
Fifty-nine consecutive patients attending rheumatology clinics with arthralgia and psoriasis were studied. Comparison groups with radiographic evidence of rheumatoid arthritis (52 patients), osteoarthritis (44) or normal hands (55) were also recorded.
Twenty-one of 59 patients with psoriasis and arthropathy had a sesamoid index>40, compared with two of 52 with rheumatoid arthritis, none of 44 with osteoarthritis and none of 55 normals.
Psoriatic arthropathy is a recognised cause of bone enlargement, usually in the phalanges due to periostitis and proliferative enthesopathy. We have confirmed that psoriatic hand arthropathy can cause significant enlargement of the thumb sesamoids, a feature which is easily quantified and may assist diagnosis.
籽骨指数最初被描述为一种辅助诊断肢端肥大症的方法。我们开展本研究以评估拇指籽骨指数在银屑病关节炎诊断中的价值。
对籽骨指数(拇指内侧籽骨的长度×宽度)进行回顾性测量,并记录如下患者的年龄和性别。银屑病患者被分为有或无手部关节病影像学证据的两组。
对59例因关节痛和银屑病就诊于风湿病诊所的连续患者进行了研究。还记录了有类风湿关节炎影像学证据的对照组(52例患者)、骨关节炎对照组(44例)或手部正常的对照组(55例)。
59例银屑病合并关节病患者中,21例籽骨指数>40,相比之下,52例类风湿关节炎患者中有2例,44例骨关节炎患者中无1例,55例正常对照者中也无1例。
银屑病关节炎是公认的导致骨质增大的原因,通常是由于骨膜炎和增殖性附着点病导致指骨增大。我们已经证实,银屑病手部关节病可导致拇指籽骨显著增大,这一特征易于量化,可能有助于诊断。