Lampen A
Lebensmitteltoxikologie, Institut für Lebensmitteltoxikologie und Chemische Analytik, Zentrum für Lebensmittelwissenschaften, Tierärztliche Hochschule Hannover.
Dtsch Tierarztl Wochenschr. 2004 Jul;111(7):292-4.
The idenfication of the human genome makes it possible to investigate complex biological issues with new molecular techniques. Platformtechnologies such as DNA-Arrays or 2-D gelelectrophoresis combined with mass spectrometry will make it possible to have a faster look from gene to the protein and to find new target genes of compounds as well as new molecular mechanisms involved. The knowledge about complex molecular signalling pathways will give a real impact to new diagnostics in food analytics. As an example reporter gene assays as screening methods in the diagnostic of food contaminants will be discussed. Additionally, another example, the Novel Food will be discussed because the molecular techniques will improve diagnostics and the risk assessment of novel foods.
人类基因组的识别使得利用新的分子技术研究复杂的生物学问题成为可能。诸如DNA芯片或二维凝胶电泳结合质谱等平台技术将使我们能够更快地从基因层面深入到蛋白质层面，找到化合物的新靶基因以及所涉及的新分子机制。关于复杂分子信号通路的知识将对食品分析中的新诊断方法产生实际影响。作为一个例子，将讨论作为食品污染物诊断筛选方法的报告基因检测。此外，还将讨论另一个例子，即新型食品，因为分子技术将改善新型食品的诊断和风险评估。
