Lorusso Giovanni D, Restrepo Santiago, Sarma Deba P
Department of Pathology, Veterans' Affairs Medical Center, New Orleans, USA.
J La State Med Soc. 2004 Jul-Aug;156(4):206-8.
Peri-renal fat necrosis is rarely encountered, especially in the absence of previous surgery, trauma, or pancreatic disease. We report a patient being followed for chronic renal insufficiency by renal ultrasound in whom a renal mass was detected. Imaging studies were suggestive of renal cell carcinoma with extra-capsular extension. Histologic study confirmed renal cell carcinoma but the radiographic impression of tumor extension into surrounding adipose tissue was explained by peri-renal fat necrosis and fibrosis. To the best of our knowledge, this is the second reported case of peri-renal fat necrosis associated with renal cell carcinoma. We propose a possible mechanism for the association.
肾周脂肪坏死很少见,尤其是在既往没有手术、创伤或胰腺疾病的情况下。我们报告了一例因慢性肾功能不全接受肾脏超声检查的患者,在该患者中检测到一个肾脏肿物。影像学检查提示肾细胞癌伴包膜外侵犯。组织学研究证实为肾细胞癌,但肿瘤延伸至周围脂肪组织的影像学表现是由肾周脂肪坏死和纤维化所致。据我们所知,这是第二例报道的与肾细胞癌相关的肾周脂肪坏死病例。我们提出了一种可能的关联机制。