Yeh Lee-Ren, Chen Clement K- H, Lai Ping-Hon
Department of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC.
J Chin Med Assoc. 2004 Jun;67(6):287-95.
The purpose of this study was to establish complete normative bone mineral density (BMD) values of Taiwanese men for anteroposterior, lateral spine, and hip.
Five-hundred and 69 healthy men (aged 20 to 88 years) were recruited to establish normal reference data of lumbar spine and hip, measured by a Hologic QDR 2000 bone densitometer. One-way analysis of variance was used to examine mean difference of BMD between different age groups. The effect of age change, body weight and height on BMD was determined by multivariate linear regression.
The peak BMD values of most anatomic sites occurred in the age 20-30 group, and were 1.017, 0.862, 0.909, 0.860, 0.993 g/cm2 for anteroposterior spine, lateral spine, femoral neck, Ward's triangle, and total hip, respectively. The BMD values then steadily decreased with increase of age. After age 60-70, there was less age-related reduction of BMD values at the anteroposterior, lateral spines and Ward's triangle. By the 8th decade, the percentage losses in the anteroposterior spine, lateral spine, femoral neck, Ward's triangle, and total hip were 12%, 22%, 30%, 45%, and 22%, respectively. The BMD values correlated better with age and body weight than with body height at all anatomic sites. The body height was insignificant in predicting the BMD values at most anatomic sites. As compared with the normative BMD value provided by the Hologic Corporation, Chinese men had lower BMD value than Caucasian at most sites except Ward's triangle. At the anteroposterior spine, the values of Chinese and Japanese men were similar, whereas at the hip and its subregions, Chinese young male population had higher bone mineral density than Japanese.
The data provided by this study may be used as normal reference values for Taiwanese men, instead of the values for Asians provided by the manufacturer.
本研究的目的是建立台湾男性腰椎前后位、侧位以及髋部的完整骨密度（BMD）正常参考值。
招募了569名健康男性（年龄在20至88岁之间），使用Hologic QDR 2000骨密度仪测量腰椎和髋部，以建立正常参考数据。采用单因素方差分析检验不同年龄组之间骨密度的平均差异。通过多元线性回归确定年龄变化、体重和身高对骨密度的影响。
大多数解剖部位的骨密度峰值出现在20 - 30岁年龄组，腰椎前后位、侧位、股骨颈、Ward三角和全髋部的骨密度峰值分别为1.017、0.862、0.909、0.860、0.993g/cm²。随后，骨密度值随年龄增长而稳步下降。60 - 70岁以后，腰椎前后位、侧位和Ward三角处与年龄相关的骨密度值下降较少。到80岁时，腰椎前后位、侧位、股骨颈、Ward三角和全髋部的骨密度损失百分比分别为12%、22%、30%、45%和22%。在所有解剖部位，骨密度值与年龄和体重的相关性优于与身高的相关性。在大多数解剖部位，身高对骨密度值的预测无显著意义。与Hologic公司提供的骨密度正常参考值相比，除Ward三角外，中国男性在大多数部位的骨密度值低于白种人。在腰椎前后位，中国男性和日本男性的值相似，而在髋部及其亚区域，中国年轻男性人群的骨密度高于日本男性。
本研究提供的数据可作为台湾男性的正常参考值，而非制造商提供的亚洲人的参考值。
