Francetti Luca, Del Fabbro Massimo, Basso Matteo, Testori Tiziano, Taschieri Silvio, Weinstein Roberto
Department of Odontology, Faculty of Medicine, Galeazzi Institute, University of Milan, Milan, Italy.
J Clin Periodontol. 2004 Oct;31(10):857-62. doi: 10.1111/j.1600-051X.2004.00566.x.
BACKGROUND/PURPOSE: This randomized clinical trial was aimed at comparing two different means of delivering chlorhexidine digluconate (CHX) for plaque control during the 2 weeks following implant surgery.
Twenty patients selected for implant therapy were randomly divided into two groups: 10 subjects used 15 ml of 0.12% CHX mouthrinse (control group) and 10 used 0.2% CHX spray (test group). Professional oral hygiene was carried out immediately before surgery. During the 14 days following surgery mechanical oral hygiene was performed only at the teeth not surgically involved. Plaque index (PI), stain index (SI), modified gingival index and taste alteration were assessed on the 7th and 14th day after surgery. The clinical parameters were evaluated at four tooth surfaces by a single examiner. Teeth proximal to surgical site and teeth not involved were statistically compared.
In both groups, the PI increased similarly, with respect to the baseline, at days 7 and 14. There was no significant difference between the two groups at either time point. On the contrary, in the control group, the SI increased significantly when compared with baseline over the 14 days both at teeth nearest to surgical sites and at not-involved sites. In the test group pigmentation was consistent only at teeth proximal to the surgical site. When considering not-involved sites, tooth staining was significantly lower in the test with respect to the control group.
The present study indicates that the efficacy of CHX spray in the post-surgical control of dental plaque is similar to that of CHX mouthwash. Tooth staining, however, is significantly lower in the spray group at sites not surgically involved. These effects might be related to the route of CHX delivery, as well as the total dose administered that was significantly lower in the spray group with respect to the rinse group.
背景/目的:本随机临床试验旨在比较在种植手术后2周内,两种不同的葡萄糖酸洗必泰(CHX)给药方式对牙菌斑的控制效果。
选取20例接受种植治疗的患者,随机分为两组:10例受试者使用15毫升0.12%的CHX漱口水(对照组),10例使用0.2%的CHX喷雾剂(试验组)。手术前即刻进行专业口腔卫生护理。在术后14天内,仅对未进行手术的牙齿进行机械口腔卫生护理。在术后第7天和第14天评估菌斑指数(PI)、染色指数(SI)、改良牙龈指数和味觉改变。由一名检查者在四个牙面评估临床参数。对手术部位附近的牙齿和未涉及手术的牙齿进行统计学比较。
在第7天和第14天,两组的PI相对于基线均有相似程度的升高。在两个时间点,两组之间均无显著差异。相反,在对照组中,与基线相比,在最靠近手术部位的牙齿和未涉及手术的部位,14天内SI均显著升高。在试验组中,仅手术部位附近的牙齿色素沉着一致。在未涉及手术的部位,试验组的牙齿染色明显低于对照组。
本研究表明,CHX喷雾剂在种植手术后控制牙菌斑的效果与CHX漱口水相似。然而,在未进行手术的部位,喷雾剂组的牙齿染色明显较低。这些效果可能与CHX的给药途径以及给药总量有关,喷雾剂组的给药总量相对于漱口水组显著更低。