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牙周手术后洗必泰喷雾剂与洗必泰漱口水对牙菌斑的控制效果比较

Chlorhexidine spray versus chlorhexidine mouthwash in the control of dental plaque after periodontal surgery.

作者信息

Francetti L, del Fabbro M, Testori T, Weinstein R L

机构信息

Dipartimento di Medicina, Chirurgia e Odontoiatria Ospedale S Paolo, Cattedra di Parodontologia, Università degli studi di Milano, Italy.

出版信息

J Clin Periodontol. 2000 Jun;27(6):425-30. doi: 10.1034/j.1600-051x.2000.027006425.x.

Abstract

BACKGROUND/AIMS: This clinical trial aimed at comparing 2 different means of delivering chlorhexidine digluconate (CHX) in the oral hygiene phase during the 2 weeks following periodontal surgery.

METHOD

40 patients were randomly divided into 2 groups: A (using CHX mouthwash) and B (using CHX spray). Professional oral hygiene was carried out immediately before surgical operation. For 7 days after surgery, group A used CHX mouthwash and group B CHX spray on the teeth involved in the surgical procedure, while mechanical oral hygiene was maintained only on the teeth not involved surgically. After suture removal, on the 7th day, patients were allowed to perform mechanical oral hygiene also on surgical sites. Plaque index (PI) and stain index (SI) were evaluated on the 7th and 14th days after the operation.

RESULTS

In both groups, PI increased similarly with respect to the baseline in surgically involved teeth, being 0.25+/-0.41 (SD) and 0.15+/-0.26, respectively, in A and B, on day 7, and 0.14+/-0.23 (A) and 0.10+/-0.22 (B), on day 14. There was no significant difference between A and B on either day 7 or 14. On the contrary, SI increased significantly in respect to the baseline over the 14 days in group A at both involved and not involved sites, while it did not differ from the baseline in group B.

CONCLUSIONS

The present results indicate that the efficacy of CHX spray in the post-surgical control of dental plaque is not different from that of CHX mouthwash. Tooth staining, on the contrary, was significantly lower in the group using CHX spray. The observed effects might be related to the way of delivering CHX and to the total dose administered, about 80% lower in group B in respect to A. Further studies are needed to validate the preliminary findings of the present study.

摘要

背景/目的:本临床试验旨在比较在牙周手术后2周的口腔卫生阶段,两种不同方式递送葡萄糖酸洗必泰(CHX)的效果。

方法

40例患者随机分为两组:A组(使用CHX漱口水)和B组(使用CHX喷雾)。在手术操作前即刻进行专业口腔卫生护理。术后7天,A组在手术涉及的牙齿上使用CHX漱口水,B组使用CHX喷雾,而仅对未进行手术的牙齿进行机械口腔卫生护理。拆线后,在第7天,患者也可对手术部位进行机械口腔卫生护理。在术后第7天和第14天评估菌斑指数(PI)和染色指数(SI)。

结果

在两组中,手术涉及牙齿的PI相对于基线均有类似增加,第7天时A组为0.25±0.41(标准差)而B组为0.15±0.26,第14天时A组为0.14±0.23、B组为0.10±0.22。在第7天或第14天,A组和B组之间均无显著差异。相反,在A组中,在涉及和未涉及的部位,SI在14天内相对于基线均显著增加,而B组与基线无差异。

结论

目前的结果表明,CHX喷雾在术后控制牙菌斑方面的效果与CHX漱口水无异。相反,使用CHX喷雾的组牙齿染色明显更低。观察到的效果可能与CHX的递送方式以及给药总量有关,B组给药总量比A组低约80%。需要进一步研究来验证本研究的初步发现。

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