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蛋白质摄入量无法通过尿尿素排泄量来估算。

Protein intake can not be estimated from urinary urea excretion.

作者信息

Kist-van Holthe tot Echten J E, Nauta J, Hop W C, de Jong M C, van Luijk W H, Ploos van Amstel S L, Roodhooft A M, Noordzij C M, Wolff E D

机构信息

Department of Paediatrics, Sophia Children's Hospital/University Hospital Rotterdam, The Netherlands.

出版信息

Pediatr Nephrol. 1992 Jan;6(1):85-7. doi: 10.1007/BF00856848.

DOI:10.1007/BF00856848
PMID:1536748
Abstract

We assessed the relationship between protein intake (calculated from a 3-day prospective dietary diary) and 24-h urinary urea excretion in 37 children with chronic renal failure. Protein intake was not restricted during the investigation period. The 24-h urinary urea excretion correlated poorly with the protein intake estimated from the dietary diary (r = 0.58). We conclude that although it is common practice to assess compliance with a protein-restricted diet in children with chronic renal failure with a dietary diary and 24-h urinary urea excretion, the value of this assessment is questionable.

摘要

我们评估了37名慢性肾衰竭儿童的蛋白质摄入量(根据3天前瞻性饮食日记计算)与24小时尿尿素排泄之间的关系。在调查期间,蛋白质摄入量未受限制。24小时尿尿素排泄与饮食日记估计的蛋白质摄入量相关性较差(r = 0.58)。我们得出结论,虽然在慢性肾衰竭儿童中用饮食日记和24小时尿尿素排泄来评估蛋白质限制饮食的依从性是常见做法,但这种评估的价值值得怀疑。

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本文引用的文献

1
[ENZYMATIC UREA DETERMINATION IN THE BLOOD AND SERUM IN THE WARBURG OPTICAL TEST].[在瓦氏光学试验中血液及血清中尿素的酶法测定]
Klin Wochenschr. 1965 Feb 1;43:174-5. doi: 10.1007/BF01484513.
2
Methods for assessing nutritional status of patients with renal failure.评估肾衰竭患者营养状况的方法。
Am J Clin Nutr. 1980 Jul;33(7):1567-85. doi: 10.1093/ajcn/33.7.1567.
3
Dietary protein intake and the progressive nature of kidney disease: the role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease.
膳食蛋白质摄入量与肾脏疾病的进展特性:血流动力学介导的肾小球损伤在衰老、肾切除及原发性肾脏疾病所致进行性肾小球硬化发病机制中的作用
N Engl J Med. 1982 Sep 9;307(11):652-9. doi: 10.1056/NEJM198209093071104.
4
Metabolic studies of low protein diets in uremia. I. Nitrogen and potassium.
Medicine (Baltimore). 1973 Nov;52(6):583-95. doi: 10.1097/00005792-197311000-00004.
5
A method for estimating nitrogen intake of patients with chronic renal failure.一种估算慢性肾衰竭患者氮摄入量的方法。
Kidney Int. 1985 Jan;27(1):58-65. doi: 10.1038/ki.1985.10.
6
The estimation of dietary protein intake in chronic renal failure.慢性肾衰竭患者膳食蛋白质摄入量的评估
Nephrol Dial Transplant. 1989;4(10):877-82. doi: 10.1093/ndt/4.10.877.
7
Nitrogen balance of uremic patients receiving branched-chain ketoacids and the hydroxy-analogue of methionine as substitutes for the respective amino acids.接受支链酮酸和蛋氨酸羟基类似物替代相应氨基酸的尿毒症患者的氮平衡。
Clin Nephrol. 1977 Aug;8(2):341-4.
8
Nitrogen balance studies with normal children.对正常儿童的氮平衡研究。
Am J Clin Nutr. 1977 Jun;30(6):939-46. doi: 10.1093/ajcn/30.6.939.