慢性苯中毒对小鼠肝脏中某些酶行为的影响。
The behaviour of some enzymes in the mouse liver due to chronic benzene intoxication.
作者信息
Kamińska O, Jonek J, Kamiński M, Koehler B, Konecki J
出版信息
Acta Histochem. 1978;62(2):209-22. doi: 10.1016/S0065-1281(78)80087-7.
PMID:153699
Abstract
- Long trem benzene action brings about a permanent decrease in oxidoreductive enzymes and active transport as well as an inactivation of the lysosomal apparatus in liver-cells. 2. Particular liver lobule zones show different sensitivity to toxic action of benzene which might result from their different role in the processes of benzene biotransformation.
摘要
- 长期接触苯会导致肝脏细胞中氧化还原酶和主动转运功能永久性下降，以及溶酶体装置失活。2. 肝脏小叶的特定区域对苯的毒性作用表现出不同的敏感性，这可能是由于它们在苯生物转化过程中的不同作用所致。
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