Vanamo K, Rintala R, Lindahl H
Department of Pediatric Surgery 2206, Kuopio University Hospital, 70211 Kuopio, Finland.
Pediatr Surg Int. 2004 Sep;20(9):692-4. doi: 10.1007/s00383-004-1275-7. Epub 2004 Sep 11.
An ideal operation for necrotising enterocolitis (NEC) would be quick and reliable, remove all nonviable bowel, minimise the loss of intestinal length, permit early restoration of intestinal continuity, and minimise the need for secondary operations. No operation currently meets all these needs. In this study we review our experience with the Santulli enterostomy in NEC. From 1992 to 1998, 19 patients (16 males, three females) underwent a Santulli enterostomy for Bell grade III NEC. The median gestational age at birth (GA) was 26 weeks (range 23-30), and the median birth weight 755 g (range 600-1095). The median patient age at operation was 10 days (range 3-59), and the median operative time was 55 min (range 25-90). Sixteen (84%) patients survived. Complications included leakage of the Santulli anastomosis in four cases, stomal necrosis in two cases, additional intestinal necrosis in two cases, leakage of a concurrent intra-abdominal anastomosis in two cases, and intestinal obstruction in four cases. Twelve patients underwent relaparotomy. Enteral feeding was started at a median of 5 days postoperatively (range 2-9), with full oral feeding possible at a median of 21 days (range 10-128). The median time until closure of the enterostomy was 48 days and the median hospital stay 87 days (range 19-197). After stomal closure, obstructive symptoms necessitated a new Santulli enterostomy in two patients and a revision of the anastomosis in one patient. Santulli enterostomy can be used to treat NEC even in very small premature babies. It enables rapid recovery of intestinal continuity and early stomal closure. However, the operation is technically demanding and carries significant morbidity.
坏死性小肠结肠炎(NEC)的理想手术应快速可靠,切除所有无活力的肠段,尽量减少肠管长度的损失,允许早期恢复肠道连续性,并尽量减少二次手术的需求。目前尚无手术能满足所有这些需求。在本研究中,我们回顾了我们在NEC中应用桑图利肠造口术的经验。1992年至1998年,19例患者(16例男性,3例女性)因贝尔Ⅲ级NEC接受了桑图利肠造口术。出生时的中位孕周(GA)为26周(范围23 - 30周),中位出生体重755克(范围600 - 1095克)。手术时患者的中位年龄为10天(范围3 - 59天),中位手术时间为55分钟(范围25 - 90分钟)。16例(84%)患者存活。并发症包括4例桑图利吻合口漏、2例造口坏死、2例额外的肠坏死、2例同时存在的腹腔内吻合口漏以及四例肠梗阻。12例患者接受了再次剖腹手术。术后中位5天(范围2 - 9天)开始肠内喂养,中位21天(范围10 - 128天)可完全经口喂养。肠造口关闭的中位时间为48天,中位住院时间为87天(范围19 - 197天)。造口关闭后,两名患者因梗阻症状需要再次行桑图利肠造口术,一名患者需要吻合口修复。即使是非常小的早产儿,桑图利肠造口术也可用于治疗NEC。它能使肠道连续性迅速恢复并早期关闭造口。然而,该手术技术要求高且并发症发生率高。