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先天性肠道畸形和产后肠道损伤中再次探讨桑图利手术:经验初步报告

Santulli Procedure Revisited in Congenital Intestinal Malformations and Postnatal Intestinal Injuries: Preliminary Report of Experience.

作者信息

Vinit Nicolas, Rousseau Véronique, Broch Aline, Khen-Dunlop Naziha, Hachem Taymme, Goulet Olivier, Sarnacki Sabine, Beaudoin Sylvie

机构信息

Department of Pediatric Surgery and Urology, Necker-Enfants Malades Hospital, APHP, 75015 Paris, France.

Faculté de Médecine Paris Centre, Université de Paris, 75006 Paris, France.

出版信息

Children (Basel). 2022 Jan 7;9(1):84. doi: 10.3390/children9010084.

Abstract

In our experience, the Santulli procedure (SP) can improve bowel recovery in congenital intestinal malformations, necrotizing enterocolitis (NEC), and bowel perforation. All cases managed at our institution using SP between 2012 and 2017 were included in this study. Forty-one patients underwent SP (median age: 39 (0-335) days, median weight: 2987 (1400-8100) g) for intestinal atresia (51%, two gastroschisis), NEC (29%), midgut volvulus (10%), Hirschsprung's disease (5%), or bowel perforation (5%), with at least one intestinal suture below the Santulli in 10% of cases. The SP was performed as a primary procedure (57%) or as a double-ileostomy reversal. Anal-stool passing occurred within a median of 9 (2-36) days for 95% of patients, regardless of the diversion level or the underlying disease. All three patients requiring repeated surgery for Santulli dysfunction had presented with stoma prolapse ( < 0.01). Stoma closure was performed after a median of 45 (14-270) days allowing efficient transit after a median of 2 (1-6) days. After a median follow-up of 2.9 (0.7-7.2) years, two patients died (cardiopathy and brain hemorrhage), full oral intake had been achieved in 90% of patients, and all survivors had normal bowel movement. Whether used as primary or secondary surgery, the SP allows rapid recovery of intestinal motility and function.

摘要

根据我们的经验,桑图利手术(SP)可促进先天性肠道畸形、坏死性小肠结肠炎(NEC)和肠穿孔患者的肠道恢复。本研究纳入了2012年至2017年间在我院接受SP治疗的所有病例。41例患者因肠闭锁(51%,2例腹裂)、NEC(29%)、中肠扭转(10%)、先天性巨结肠(5%)或肠穿孔(5%)接受了SP手术(中位年龄:39(0 - 335)天,中位体重:2987(1400 - 8100)g),10%的病例在桑图利下方至少有一处肠缝合。SP作为一期手术(57%)或双回肠造口术回纳进行。95%的患者中位9(2 - 36)天出现肛门排便,与转流水平或基础疾病无关。所有3例因桑图利功能障碍需要再次手术的患者均出现造口脱垂(<0.01)。中位45(14 - 270)天后进行造口关闭,中位2(1 - 6)天后实现有效排便。中位随访2.9(0.7 - 7.2)年后,2例患者死亡(心脏病和脑出血),90%的患者实现完全经口进食,所有幸存者排便正常。无论作为一期手术还是二期手术,SP均能使肠道运动和功能快速恢复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5277/8774359/0d03ea767b09/children-09-00084-g001.jpg

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