Eggeling S, Kaiser D
Abteilung für Thoraxchirurgie, Lungenklinik Heckeshorn, Zentralklinik Emil v. Behring, Berlin.
MMW Fortschr Med. 2004 May 20;146(21):40-2.
Malignant pleural effusion is a complication of malignant diseases that has an appreciable negative impact on the patient's quality of life. In view of the greatly reduced life expectancy of between 3 and 12 months (median), diagnostic and therapeutic management must be orientated to the principles of palliation. Diagnostic measures comprise cytological/histological confirmation of the malignant effusion and, where necessary, of the underlying malignant disease and the extent of the intrathoracic tumor growth. In view of the tendency of malignant pleural effusion to relapse, pleurodesis is indicated, which is most effectively accomplished by video-assisted thoracoscopic talcum poudrage.
恶性胸腔积液是恶性疾病的一种并发症,对患者的生活质量有明显的负面影响。鉴于患者预期寿命大幅缩短至3至12个月(中位数),诊断和治疗管理必须遵循姑息治疗原则。诊断措施包括对恶性胸腔积液进行细胞学/组织学确诊,必要时对潜在恶性疾病及胸腔内肿瘤生长范围进行确诊。鉴于恶性胸腔积液有复发倾向,建议进行胸膜固定术,而电视辅助胸腔镜滑石粉喷洒是最有效的胸膜固定术方法。