Colt H G
Division of Pulmonary and Critical Care Medicine, University of California San Diego, USA.
Clin Chest Med. 1995 Sep;16(3):505-18.
Thoracoscopy has been around for decades, advocated by some, but until recently, ignored by many. Not surprisingly, its diagnostic and therapeutic efficacy in patients with suspected or proven malignant pleural effusions has withstood the test of time. Today, the potential benefits of thoracoscopy must be weighed against its cost in patients with limited life expectancy. Although diagnostic thoracoscopy requires only overnight hospitalization, pleurodesis imposes a longer hospital stay. The discomfort of an indwelling chest tube, the need for hospitalization, and the financial burden of thoracoscopic procedures compared with less-invasive means of pleural investigation and pleurodesis must be taken into account on an individual basis. Thoracoscopy should not be performed for the sake of intervention. Its indications and all diagnostic or therapeutic alternatives should always be carefully examined. Its role, however, in the diagnosis and treatment of patients with malignant pleural effusions is undeniable. The diagnostic accuracy of thoracoscopic pleural biopsy is excellent. Several studies demonstrate that thoracoscopic talc pleurodesis is more frequently successful than other methods of pleurodesis. As a staging procedure, thoracoscopy helps determine extent of disease, and possibly, prognosis in patients with metastatic pleural carcinomatosis, lung cancer, and malignant mesothelioma. As this procedure is increasingly rediscovered by our medical and surgical communities, greater clinical and experimental investigation aimed at establishing successful management strategies in patients with malignant pleural effusions will hopefully occur.
胸腔镜已经存在了几十年,虽有一些人提倡,但直到最近,仍被许多人忽视。毫不奇怪,它在疑似或确诊恶性胸腔积液患者中的诊断和治疗效果经受住了时间的考验。如今,对于预期寿命有限的患者,必须权衡胸腔镜检查的潜在益处与其成本。虽然诊断性胸腔镜检查仅需住院一晚,但胸膜固定术会使住院时间更长。与侵入性较小的胸膜检查和胸膜固定术方法相比,留置胸管的不适、住院需求以及胸腔镜手术的经济负担都必须根据个体情况加以考虑。不应为了干预而进行胸腔镜检查。其适应证以及所有诊断或治疗替代方案都应始终仔细审查。然而,它在恶性胸腔积液患者的诊断和治疗中的作用是不可否认的。胸腔镜胸膜活检的诊断准确性极佳。多项研究表明,胸腔镜滑石粉胸膜固定术比其他胸膜固定术方法更常取得成功。作为一种分期检查,胸腔镜有助于确定转移性胸膜癌、肺癌和恶性间皮瘤患者的疾病范围以及可能的预后。随着我们的医学和外科界越来越多地重新发现这一检查方法,有望针对恶性胸腔积液患者开展更多旨在确立成功管理策略的临床和实验研究。