Ribeiro J M C, Topalis P, Louis C
Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892-0425, USA.
Insect Mol Biol. 2004 Oct;13(5):449-57. doi: 10.1111/j.0962-1075.2004.00503.x.
The proteome of the mosquito Anopheles gambiae was organized on a hyperlinked spreadsheet format containing one protein per row and several pieces of information in each column. The information for each protein ranges from the presence or absence of signal peptide indicative of secretion, presence of transmembrane domains, similarities to several databases, chromosomal location, and relatedness to other An. gambiae proteins, etc. Hosted by AnoBase (http://www.anobase.org/), the whole spreadsheet or segments of it can be downloaded or searched from http://www.anobase.org/AnoBase/Genes/Ano-Xcel by the scientist dealing with the annotation of proteome subsets such as those deriving from transcriptomes, nucleotide microarrays or high throughput mass spectrometry data.
冈比亚按蚊的蛋白质组以超链接电子表格形式呈现,每行包含一种蛋白质,每列包含若干信息。每种蛋白质的信息包括是否存在指示分泌的信号肽、跨膜结构域的存在情况、与多个数据库的相似性、染色体定位以及与其他冈比亚按蚊蛋白质的相关性等。该电子表格由AnoBase(http://www.anobase.org/)托管,从事蛋白质组子集注释(如源自转录组、核苷酸微阵列或高通量质谱数据的子集)的科学家可从http://www.anobase.org/AnoBase/Genes/Ano-Xcel下载整个电子表格或其部分内容,也可在该网站进行搜索。