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美洲大蠊脂多糖结合蛋白作为调理素的功能。

Function of the lipopolysaccharide-binding protein of Periplaneta americana as an opsonin.

作者信息

Jomori T, Natori S

机构信息

Faculty of Pharmaceutical Sciences, University of Tokyo, Japan.

出版信息

FEBS Lett. 1992 Jan 27;296(3):283-6. doi: 10.1016/0014-5793(92)80305-z.

DOI:10.1016/0014-5793(92)80305-z
PMID:1537405
Abstract

Previously, we reported the purification of an LPS-binding protein from the hemolymph of the American cockroach that was specific for E. coli LPS. In this study we found that this protein participated in the clearance of E. coli cells injected into the abdominal cavity of the cockroach, and that hemocytes ingested E. coli cells treated with this LPS-binding protein in vitro. These findings suggest that this LPS-binding protein acts as an opsonin.

摘要

此前,我们报道了从美国蟑螂血淋巴中纯化出一种对大肠杆菌脂多糖具有特异性的脂多糖结合蛋白。在本研究中,我们发现该蛋白参与了注入蟑螂腹腔的大肠杆菌细胞的清除过程,并且血细胞在体外摄取了用这种脂多糖结合蛋白处理过的大肠杆菌细胞。这些发现表明这种脂多糖结合蛋白起到了调理素的作用。

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Function of the lipopolysaccharide-binding protein of Periplaneta americana as an opsonin.美洲大蠊脂多糖结合蛋白作为调理素的功能。
FEBS Lett. 1992 Jan 27;296(3):283-6. doi: 10.1016/0014-5793(92)80305-z.
2
Purification and characterization of lipopolysaccharide-binding protein from hemolymph of American cockroach Periplaneta americana.从美洲大蠊血淋巴中纯化和鉴定脂多糖结合蛋白
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Molecular cloning of cDNA for lipopolysaccharide-binding protein from the hemolymph of the American cockroach, Periplaneta americana. Similarity of the protein with animal lectins and its acute phase expression.从美洲大蠊(Periplaneta americana)血淋巴中克隆脂多糖结合蛋白cDNA。该蛋白与动物凝集素的相似性及其急性期表达。
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