Jomori T, Natori S
Faculty of Pharmaceutical Sciences, University of Tokyo, Japan.
FEBS Lett. 1992 Jan 27;296(3):283-6. doi: 10.1016/0014-5793(92)80305-z.
Previously, we reported the purification of an LPS-binding protein from the hemolymph of the American cockroach that was specific for E. coli LPS. In this study we found that this protein participated in the clearance of E. coli cells injected into the abdominal cavity of the cockroach, and that hemocytes ingested E. coli cells treated with this LPS-binding protein in vitro. These findings suggest that this LPS-binding protein acts as an opsonin.
此前,我们报道了从美国蟑螂血淋巴中纯化出一种对大肠杆菌脂多糖具有特异性的脂多糖结合蛋白。在本研究中,我们发现该蛋白参与了注入蟑螂腹腔的大肠杆菌细胞的清除过程,并且血细胞在体外摄取了用这种脂多糖结合蛋白处理过的大肠杆菌细胞。这些发现表明这种脂多糖结合蛋白起到了调理素的作用。