On Arzu Yağiz, Uludağ Burhanettin, Taşkiran Emin, Ertekin Cumhur
Ege University Medical School, Department of Physical Medicine and Rehabilitation, Bornova, Izmir, Turkey.
Neurorehabil Neural Repair. 2004 Sep;18(3):127-33. doi: 10.1177/0888439004269030.
To assess the effects of chronic knee pain on neural control of the nearby quadriceps muscle.
Motor-evoked potentials (MEP) in response to transcranial magnetic stimulation (TMS) of the motor cortex, maximal M responses, patellar tendon responses, and EMG activity during maximal isometric contraction were recorded from the right vastus medialis oblique (VMO) and vastus lateralis (VL) muscles in 13 patients with chronic patellofemoral pain syndrome (PPS) and 13 healthy volunteers. MEP and maximal M responses were also recorded from the right extensor digitorum brevis (EDB) muscle.
MEP amplitudes from VMO and VL were larger in patients with PPS than in controls. On the other hand, maximal M responses, EMG activity with maximal voluntary contraction, and tendon responses were smaller in patients than in controls. Motor-evoked responses and maximal M responses of the EDB muscle did not show significant difference between the 2 groups.
These results indicate that chronic knee pain modulates central motor control of an adjacent muscle.
评估慢性膝关节疼痛对附近股四头肌神经控制的影响。
记录了13例慢性髌股疼痛综合征（PPS）患者和13名健康志愿者右侧股内侧斜肌（VMO）和股外侧肌（VL）在接受运动皮层经颅磁刺激（TMS）时的运动诱发电位（MEP）、最大M反应、髌腱反应以及最大等长收缩时的肌电图（EMG）活动。还记录了右侧趾短伸肌（EDB）的MEP和最大M反应。
PPS患者VMO和VL的MEP波幅大于对照组。另一方面，患者的最大M反应、最大自主收缩时的EMG活动以及腱反应均小于对照组。两组之间EDB肌肉的运动诱发电反应和最大M反应无显著差异。
这些结果表明慢性膝关节疼痛会调节相邻肌肉的中枢运动控制。
