Hu C H, Xu F Y, Wang K, Pearson A N, Pearson G D
Department of Biochemistry and Biophysics, Oregon State University, Corvallis 97331.
Gene. 1992 Jan 15;110(2):145-50. doi: 10.1016/0378-1119(92)90641-2.
A special class of panhandles (hairpin or foldback structures) arising from the replication of symmetrical adenovirus (Ad) minichromosome dimers and oligomers have been identified by two-dimensional gel electrophoresis. Hairpins provide evidence for replicative intermediates in the pathway for Ad complementary-strand synthesis. Furthermore, larger inverted sequences give Ad minichromosomes a replicative advantage.
通过二维凝胶电泳已鉴定出一类特殊的锅柄结构（发夹或折返结构），其源自对称腺病毒（Ad）微型染色体二聚体和寡聚体的复制。发夹为Ad互补链合成途径中的复制中间体提供了证据。此外，更大的反向序列赋予Ad微型染色体复制优势。
