Abe Hajime, Hanasawa Kazuyoshi, Naitoh Hiroyuki, Endo Yoshihiro, Tani Tohru, Kushima Ryoji
Department of Surgery, Shiga University of Medical Science, 520-2192, Otsu, Seta-Tsukinowa, Japan.
Int J Clin Oncol. 2004 Aug;9(4):334-8. doi: 10.1007/s10147-004-0401-9.
A rare case of invasive ductal carcinoma within a fibroadenoma of the breast in a 42-year-old woman is reported. The patient had a well-defined mass, measuring 6.0 x 5.0 cm, in the upper lateral quadrant of the left breast. Physical examination suggested fibroadenoma. Ultrasonography and mammography revealed some malignant findings. Needle biopsy demonstrated fibroadenoma. Frozen section revealed invasive ductal carcinoma, scirrhous type, arising in a fibroadenoma; muscle-preserving mastectomy was performed. Only 16 cases of carcinoma within a fibroadenoma of the breast have been reported in the literature in Japan. Carcinoma in a fibroadenoma should be treated on the basis of the therapeutic criteria for ordinary carcinoma.
报告了一例42岁女性乳腺纤维腺瘤内发生浸润性导管癌的罕见病例。患者左乳外上象限有一个边界清晰的肿块，大小为6.0×5.0厘米。体格检查提示为纤维腺瘤。超声和乳腺钼靶检查发现了一些恶性征象。针吸活检显示为纤维腺瘤。冰冻切片显示在纤维腺瘤内发生了硬癌型浸润性导管癌；遂行保乳根治术。在日本文献中仅报道了16例乳腺纤维腺瘤内发生癌的病例。纤维腺瘤内的癌应根据普通癌的治疗标准进行治疗。
