Pathology Department, Afzalipour Medical School, Kerman, Iran.
Arch Iran Med. 2013 Jun;16(6):366-8.
Fibroadenoma is a common benign tumor observed during the second and third decades of life. Malignancy transformation in the epithelial component of a fibroadenoma is rare and can occur 20 years after its diagnosis. Mammographic findings in this phenomenon include indistinct margins and microcalcifications. Here we present a 58-year-old woman with a mobile, lateral upper quadrant mass that was rather firm when palpated. The mammography showed a lobulated mass without calcification suggestive of a benign process, most probably fibroadenoma. However the excisional biopsy contained both an intracanalicular fibroadenoma and invasive ductal carcinoma with mucinous components.
纤维腺瘤是一种常见的良性肿瘤，通常发生在生命的第二和第三个十年。纤维腺瘤上皮成分的恶性转化很少见，通常在诊断后 20 年发生。这种现象的乳房 X 线摄影表现包括边界模糊和微钙化。在此，我们介绍一位 58 岁女性，其可触及的乳房外上象限活动肿块，触诊时质地较硬。乳房 X 线摄影显示边界不清的分叶状肿块，无钙化，提示良性病变，最可能是纤维腺瘤。然而，切除活检包含管内型纤维腺瘤和浸润性导管癌伴黏液成分。
