Menon Geetha V, Sloboda Ron S
Department of Physics, University of Alberta, Edmonton, Alberta T6G 2E1, Canada.
Med Phys. 2004 Aug;31(8):2300-12. doi: 10.1118/1.1767694.
Electronic portal imaging devices (EPIDs) are being increasingly employed to make therapy verification and dose measurements in the clinic. In this work, we investigate the use of an amorphous silicon (a-Si) EPID to verify the accuracy of compensator fabrication and mounting. Compensator thickness estimates on a two-dimensional grid were calculated from the primary component of transmission obtained by subtracting a modeled scatter component from the total transmission measured with the EPID. The primary component was related to the thickness via an exponential relation that includes beam hardening. Implementation of the method involved determination of: (i) a calibration curve relating EPID pixel values to energy fluence for open and attenuated fields, which was found to be linear for open fields but to have a small quadratic component for attenuated beams; (ii) EPID scatter factors to account for field size effects, which exhibited a small dependence on compensator thickness and field size; (iii) the attenuation coefficient of the steel shot compensator material, which varied slightly with off-axis distance and field size, and (iv) an analytical model to predict scatter from the compensator, which was calculated to be <4% at the standard EPID imaging distance of 140 cm. Thickness distributions were then measured for several types of attenuators including flat, test, and clinical compensators. Although uncertainties associated with compensator manufacturing were non-negligible and made assessment of thickness measurement uncertainty difficult, we estimate the latter to be approximately 0.5 mm for steel shot compensators of thickness <4 cm.
电子射野影像装置(EPID)在临床上越来越多地用于治疗验证和剂量测量。在本研究中,我们研究了使用非晶硅(a-Si)EPID来验证补偿器制作和安装的准确性。通过从EPID测量的总透射率中减去建模的散射分量而获得的透射率主要成分,计算二维网格上的补偿器厚度估计值。主要成分通过包含束硬化的指数关系与厚度相关。该方法的实施涉及确定:(i)将EPID像素值与开放和衰减射野的能量注量相关联的校准曲线,发现该曲线对于开放射野是线性的,但对于衰减射束有一个小的二次分量;(ii)考虑射野大小效应的EPID散射因子,其对补偿器厚度和射野大小的依赖性较小;(iii)钢珠补偿器材料的衰减系数,其随离轴距离和射野大小略有变化,以及(iv)预测补偿器散射的解析模型,在140 cm的标准EPID成像距离处计算得出该散射小于4%。然后测量了几种类型衰减器的厚度分布,包括平板、测试和临床补偿器。尽管与补偿器制造相关的不确定性不可忽略,并且难以评估厚度测量的不确定性,但我们估计对于厚度<4 cm的钢珠补偿器,后者约为0.5 mm。