虫媒病毒病的传播循环、宿主范围、进化及出现

Weaver Scott C, Barrett Alan D T

Department of Pathology, Microbiology and Immunology, Center for Biodefense and Emerging Infectious Diseases, University of Texas Medical Branch, Galveston, Texas 77555-0609, USA.

Nat Rev Microbiol. 2004 Oct;2(10):789-801. doi: 10.1038/nrmicro1006.

Many pandemics have been attributed to the ability of some RNA viruses to change their host range to include humans. Here, we review the mechanisms of disease emergence that are related to the host-range specificity of selected mosquito-borne alphaviruses and flaviviruses. We discuss viruses of medical importance, including Venezuelan equine and Japanese encephalitis viruses, dengue viruses and West Nile viruses.

许多大流行病都归因于一些RNA病毒改变其宿主范围以包括人类的能力。在此，我们综述了与某些蚊媒甲病毒和黄病毒的宿主范围特异性相关的疾病出现机制。我们讨论了具有医学重要性的病毒，包括委内瑞拉马脑炎病毒、日本脑炎病毒、登革病毒和西尼罗河病毒。