Teramoto T, Watanabe H, Ito K, Omata Y, Furukawa T, Shimoda K, Hoshino M, Nagao T, Naito S
Department of Internal Medicine, Teikyo University School of Medicine, Itabashi-ku, Tokyo 173-8605, Japan.
Clin Nutr. 2004 Oct;23(5):1122-6. doi: 10.1016/j.clnu.2004.02.005.
The long-term effects of dietary diacylglycerol (DAG) on body fat and lipid metabolism were studied in patients undergoing hemodialysis (HD).
Ten patients (seven males, three females) ranging in age from 40 to 64 years were enrolled. During the test period, 9.8 g of DAG was ingested per day for 3 months.
Body mass index did not change throughout the study. The abdominal fat area measured by CT scan decreased significantly at 3 months, and increased significantly 3 months after completion of the DAG ingestion period. The serum composition of very low-density lipoprotein (VLDL) decreased significantly at 3 months and high-density lipoprotein (HDL) increased significantly at 3 months; these were determined using polyacrylamide gel electrophoresis. Serum lipoprotein (a) decreased significantly at 3 months.
Our study showed that 3-month ingestion of DAG reduced the amount of abdominal fat and improved serum lipid profiles in free-living HD patients.
研究膳食二酰甘油（DAG）对接受血液透析（HD）患者体脂和脂质代谢的长期影响。
招募了10名年龄在40至64岁之间的患者（7名男性，3名女性）。在测试期间，每天摄入9.8克DAG，持续3个月。
在整个研究过程中，体重指数没有变化。通过CT扫描测量的腹部脂肪面积在3个月时显著下降，在DAG摄入期结束3个月后显著增加。使用聚丙烯酰胺凝胶电泳测定，极低密度脂蛋白（VLDL）的血清成分在3个月时显著下降，高密度脂蛋白（HDL）在3个月时显著增加。血清脂蛋白（a）在3个月时显著下降。
我们的研究表明，在自由生活的HD患者中，摄入3个月的DAG可减少腹部脂肪量并改善血脂谱。
