Lemke A-J, Kazi I, Landeck L M, Zaspel U, Hosten N, Felix R
Universitätsklinikum Charité, Campus Virchow-Klinikum, Klinik für Strahlenheilkunde.
Rofo. 2004 Oct;176(10):1436-46. doi: 10.1055/s-2004-813411.
Over the last decade, MRI has become the standard procedure for the diagnosis of orbital masses. Purpose of the study was to evaluate criteria for differential diagnosis for intraconal masses on MRI in a large patient group.
In a retrospective study, MR examinations of 78 patients with intraconal masses were evaluated. All examinations were performed using surface coils for high spatial resolution. Signal behavior on T2-WI and T1-WI before and after contrast application as well as further tumor characteristics (i. e., shape, size, position, delineation and infiltration) were evaluated. Every diagnosis was proven by histopathological results from extirpation (n = 18) or biopsy (n = 22), or confirmed by other imaging modalities (n = 13) or clinical course (n = 25).
Different tumor characteristics are helpful in the differentiation between cavernous hemangioma, lymphangioma, varices, AV malformations and solid tumors. Due to overlapping in the imaging appearance, the differentiation between inflammatory pseudotumor, lymphoma and orbital metastasis was more difficult.
While high resolution MRI using surface coils allows differentiation between the typical vascular tumors, the differentiation between solid tumors is more difficult. Thus, a histopathologic verification of the diagnosis is necessary in solid tumors.
在过去十年中,MRI已成为诊断眼眶肿块的标准程序。本研究的目的是在一大组患者中评估MRI上圆锥内肿块的鉴别诊断标准。
在一项回顾性研究中,对78例圆锥内肿块患者的MR检查进行了评估。所有检查均使用表面线圈以获得高空间分辨率。评估了T2加权成像(T2-WI)和T1加权成像(T1-WI)在注射对比剂前后的信号表现以及其他肿瘤特征(即形状、大小、位置、边界和浸润情况)。每个诊断均通过摘除术(n = 18)或活检(n = 22)的组织病理学结果得到证实,或通过其他成像方式(n = 13)或临床病程(n = 25)得到确认。
不同的肿瘤特征有助于区分海绵状血管瘤、淋巴管瘤、静脉曲张、动静脉畸形和实体瘤。由于影像学表现存在重叠,炎性假瘤、淋巴瘤和眼眶转移瘤之间的鉴别更为困难。
虽然使用表面线圈的高分辨率MRI能够区分典型的血管性肿瘤,但实体瘤之间的鉴别更为困难。因此,实体瘤的诊断需要组织病理学验证。