Department of Otolaryngology, Head and Neck Surgery, University Hospital Giessen and Marburg, Marburg, Germany.
Br J Ophthalmol. 2010 Dec;94(12):1653-6. doi: 10.1136/bjo.2009.177147. Epub 2010 May 21.
Orbital cavernomas are low-flow vascular malformations that are the most common benign neoplasms of the orbit in adults, typically becoming symptomatic in the middle age.
The medical records of six patients with clinically suspected orbital cavernomas receiving elective surgical excision were analysed concerning symptoms, physical findings, treatment results and visual outcome. The pathologic slides were evaluated, and additional immunohistochemical stains were done if necessary to obtain diagnosis.
Histologic evaluation revealed three of six cases not being cavernomas, although the clinical and macroscopic findings were consistent with orbital cavernomas. Two of them were haemorrhagic lymphangiomas, and one was a solitary fibrous tumour.
Haemorrhagic lymphangiomas and other vascular tumours may mimic orbital cavernomas regarding anamnesis, radiologic and intraoperative findings and gross examination. Therefore, exact histologic evaluation is necessary to get the correct diagnosis.
眼眶海绵状血管瘤是低流量血管畸形,是成年人眼眶中最常见的良性肿瘤,通常在中年出现症状。
对 6 例临床疑似接受择期手术切除的眼眶海绵状血管瘤患者的病历进行分析,内容包括症状、体格检查、治疗结果和视力结果。评估病理切片,如果需要,进行额外的免疫组织化学染色以获得诊断。
组织学评估显示 6 例中有 3 例并非海绵状血管瘤,尽管临床和大体检查结果与眼眶海绵状血管瘤一致。其中 2 例为出血性淋巴管瘤,1 例为孤立性纤维瘤。
出血性淋巴管瘤和其他血管肿瘤在病史、影像学和术中发现以及大体检查方面可能与眼眶海绵状血管瘤相似。因此,需要进行确切的组织学评估以获得正确的诊断。