Bernal Kerry L, Fahmy Lylia, Remmenga Steven, Bridge Julia, Baker John
Department of Pathology/Microbiology, University of Nebraska Medical Center, Omaha, Nebraska 58198, USA.
Gynecol Oncol. 2004 Oct;95(1):243-6. doi: 10.1016/j.ygyno.2004.06.049.
Embryonal rhabdomyosarcoma (sarcoma botryoides) of the female genital tract is rare in the cervix. It tends to occur in children and young women, and appears to have a better prognosis than sarcoma botryoides of the vagina and uterus.
We report a case of embryonal rhabdomyosarcoma (sarcoma botryoides) presenting as a cervical polyp in a 19-year-old female. The tumor was composed of rhabdomyoblasts of varying differentiation dispersed within a loose, myxoid stroma, and formed a distinct 'cambium' layer beneath the epithelium. The patient was successfully treated with fertility-sparing surgery and adjuvant chemotherapy.
Awareness of this uncommon lesion in this site and its clinical implications is important to avoid misdiagnosis. Therapy has recently inclined towards conservative treatment.
女性生殖道胚胎性横纹肌肉瘤（葡萄状肉瘤）在宫颈中罕见。它倾向于发生在儿童和年轻女性中，并且似乎比阴道和子宫的葡萄状肉瘤预后更好。
我们报告一例19岁女性胚胎性横纹肌肉瘤（葡萄状肉瘤）表现为宫颈息肉的病例。肿瘤由散在于疏松黏液样基质中的不同分化程度的横纹肌母细胞组成，并在上皮下形成明显的“生发”层。患者通过保留生育功能的手术和辅助化疗成功治愈。
认识到该部位这种罕见病变及其临床意义对于避免误诊很重要。最近治疗倾向于保守治疗。
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