The Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The Ohio State University College of Medicine, M-210 Starling-Loving, 320 West Tenth Avenue, Columbus, OH, 43210-1228, USA.
J Robot Surg. 2008 Sep;2(3):197-200. doi: 10.1007/s11701-008-0095-5. Epub 2008 Aug 5.
Mullerian rhabdomyosarcoma (RMS) is a rare malignancy most commonly diagnosed in childhood and adolescence. RMS of the female genital tract is often difficult to diagnose. Treatment includes chemotherapy with adjuvant surgery and/or radiation therapy reserved for persistent disease. We report a case of an 18-year-old African-American female who presented with severe menometrorrhagia, and was diagnosed with embryonal rhabdomyosarcoma of the uterus. After vincristine, dactinomycin, and cyclophosphamide failed to eradicate the central tumor, she underwent a robotic radical hysterectomy and pelvic lymphadenectomy. Mullerian rhabdomyosarcoma was once managed with multimodality therapy that often included ultraradical surgery including total pelvic exenteration. Surgical procedures that were exclusively performed via large abdominal incisions can now be completed with minimally invasive techniques. Robotic surgery can be safely and successfully applied to radical hysterectomy and lymphadenectomy for uterine rhabdomyosarcoma.
苗勒氏横纹肌肉瘤(RMS)是一种罕见的恶性肿瘤,最常见于儿童和青少年期诊断。女性生殖道 RMS 常常难以诊断。治疗包括化疗,辅助手术和/或放疗,保留用于持续疾病。我们报告了一例 18 岁的非裔美国女性,她表现为严重的经间出血,并被诊断为子宫胚胎横纹肌肉瘤。长春新碱、放线菌素 D 和环磷酰胺未能根除中央肿瘤后,她接受了机器人根治性子宫切除术和盆腔淋巴结切除术。苗勒氏横纹肌肉瘤曾经采用多模式治疗,通常包括超根治性手术,包括全盆腔脏器切除术。曾经仅通过大的腹部切口进行的手术现在可以通过微创技术完成。机器人手术可以安全有效地应用于子宫横纹肌肉瘤的根治性子宫切除术和淋巴结切除术。