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宫颈葡萄状肉瘤患者行息肉切除术后辅助化疗——病例报告及文献复习

Polypectomy followed by adjuvant chemotherapy in a patient with sarcoma botryoides of the uterine cervix--case report and review of the literature.

作者信息

Sobiczewski Piotr, Dańska-Bidzińska Anna, Miedzinska Magdalena, Olszewski Wojciech, Bidzinski Mariusz

机构信息

Gynecologic Oncology Department, The Maria Sklodowska-Curie Memorial Cancer Center, Warsaw, Poland.

出版信息

Ginekol Pol. 2011 Nov;82(11):857-61.

Abstract

BACKGROUND

Embryonal rhabdomyosarcoma in a form of a polyp of the uterine cervix occurs mainly in young women in their second decade of life. The characteristic microscopic features are: the submucosal cambium layer and the presence of rhabdomyoblasts in the stroma. So far the treatment has not been well defined and ranges from conservative to radical surgery

CASE

The presented case is a 22-year old woman with cervical polyp. Polypectomy with D&C was performed in 2005 and the microscopic examination revealed rhabdomyosarcoma botryoides. Detailed examination diagnosed stage 1a of the disease. The patient received 6 cycles of chemotherapy (Vincristine and Actinomycin).

CONCLUSION

Conservative treatment may be considered in young women with favorable prognostic factors who wish to preserve their fertility Polypectomy followed by chemotherapy is a possible option for such patients.

摘要

背景

子宫颈息肉样胚胎性横纹肌肉瘤主要发生于20岁左右的年轻女性。其特征性微观表现为:黏膜下层生发层以及间质中存在横纹肌母细胞。到目前为止,治疗方法尚未明确界定,范围从保守手术到根治性手术。

病例

该病例为一名22岁患有宫颈息肉的女性。2005年进行了息肉切除术及刮宫术,显微镜检查显示为葡萄状横纹肌肉瘤。详细检查诊断为疾病1a期。患者接受了6个周期的化疗(长春新碱和放线菌素)。

结论

对于希望保留生育能力且预后因素良好的年轻女性,可考虑保守治疗。息肉切除术后化疗是这类患者的一种可行选择。

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