Bisgaard T, Støckel M, Klarskov B, Kehlet H, Rosenberg J
Department of Surgical Gastroenterology, H:S Hvidovre Hospital, University of Copenhagen, Hvidovre, University of Copenhagen, Hellerup, Denmark.
Br J Surg. 2004 Nov;91(11):1473-8. doi: 10.1002/bjs.4720.
The aim of this study was to define factors that limit a short period of convalescence and to characterize the pain experienced after laparoscopic fundoplication.
This prospective study included 60 consecutive patients who underwent uncomplicated laparoscopic Nissen fundoplication for gastro-oesophageal reflux disease. Patients were recommended to convalesce for 2 days after operation. Duration of convalescence, dysphagia, fatigue, nausea, vomiting and different pain components were registered daily during the first week and on days 10 and 30 after fundoplication.
Thirty-nine patients took a median of 13 (range 3-41) days off work and 60 stayed away from recreational activity for a median of 4 (range 1-22) days. Pain, fatigue and plans made before operation were the main contributors to prolonged convalescence. Some 30-40 per cent of the patients reported moderate or severe dysphagia during the study period. Fatigue scores were significantly increased for 6 days after surgery (P < 0 . 001). Visceral pain dominated over incisional and shoulder pain throughout the study. At day 30, 17 per cent of the patients reported moderate or severe visceral pain.
Pain and dysphagia are significant problems after uncomplicated total laparoscopic fundoplication. The time taken off work and away from recreational activity exceeded the recommended 2 days of convalescence, justifying further efforts to optimize early clinical outcome after total laparoscopic fundoplication.
本研究旨在确定限制短期康复的因素,并描述腹腔镜胃底折叠术后所经历的疼痛。
这项前瞻性研究纳入了60例因胃食管反流病接受无并发症腹腔镜尼氏胃底折叠术的连续患者。建议患者术后康复2天。在术后第一周以及胃底折叠术后第10天和第30天,每天记录康复时间、吞咽困难、疲劳、恶心、呕吐及不同疼痛成分。
39例患者平均休假13天(范围3 - 41天),60例患者平均4天(范围1 - 22天)未参加娱乐活动。疼痛、疲劳及术前计划是康复时间延长的主要因素。在研究期间,约30% - 40%的患者报告有中度或重度吞咽困难。术后6天疲劳评分显著升高(P < 0.001)。在整个研究过程中,内脏痛比切口痛和肩痛更为突出。在第30天,17%的患者报告有中度或重度内脏痛。
无并发症的全腹腔镜胃底折叠术后,疼痛和吞咽困难是显著问题。休假时间和未参加娱乐活动的时间超过了建议的2天康复期,这表明有必要进一步努力优化全腹腔镜胃底折叠术后的早期临床结局。