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食管动力障碍与腹腔镜下尼氏胃底折叠术后不良预后无关。

Oesophageal dysmotility is not associated with poor outcome after laparoscopic Nissen fundoplication.

作者信息

Beckingham I J, Cariem A K, Bornman P C, Callanan M D, Louw J A

机构信息

Department of Surgery, Queen's Medical Centre, Nottingham, UK.

出版信息

Br J Surg. 1998 Sep;85(9):1290-3. doi: 10.1046/j.1365-2168.1998.00832.x.

Abstract

BACKGROUND

Nissen fundoplication has become the standard operation in the surgical management of gastro-oesophageal reflux disease. Postoperative dysphagia is thought to occur more commonly in patients with oesophageal dysmotility and it has been recommended that fundoplication be modified or avoided in these patients. The aim of this study was to determine the outcome of patients with normal motility and dysmotility undergoing laparoscopic Nissen fundoplication.

METHODS

This was a single-centre prospective cohort study with 1-year follow-up, using dysphagia as the main outcome variable. Of 81 patients who underwent laparoscopic surgery, 48 had normal motility and 33 had oesophageal dysmotility (defined as percentage peristalsis, using ten wet swallows, of 50 per cent or less and/or a mean distal pressure of less than 40 mmHg).

RESULTS

Dysphagia was present before operation in 14 of 48 patients with normal motility and 15 of 33 in the dysmotility group (P=0.2). At 3-month follow-up, new or worse dysphagia was present in 13 of 48 patients in the normal group and four of 33 in the dysmotility group (P=0.17). At 1 year the incidence of dysphagia was six of 48 in the normal group and five of 33 in the dysmotility group (P=0.9).

CONCLUSION

Preoperative manometric assessment of oesophageal motility does not correlate with postoperative outcome, and oesophageal dysmotility should not be regarded as a contraindication to laparoscopic Nissen fundoplication.

摘要

背景

nissen胃底折叠术已成为胃食管反流病外科治疗的标准术式。术后吞咽困难被认为在食管动力障碍患者中更常见,有人建议在这些患者中对胃底折叠术进行改良或避免实施该手术。本研究的目的是确定接受腹腔镜nissen胃底折叠术的动力正常和动力障碍患者的手术结果。

方法

这是一项单中心前瞻性队列研究,随访1年,以吞咽困难作为主要结局变量。在81例行腹腔镜手术的患者中,48例动力正常,33例存在食管动力障碍(定义为用十次湿吞咽动作时蠕动百分比为50%或更低和/或平均远端压力小于40mmHg)。

结果

48例动力正常的患者中有14例术前存在吞咽困难,动力障碍组33例中有15例(P=0.2)。在3个月随访时,正常组48例中有13例出现新的或更严重的吞咽困难,动力障碍组33例中有4例(P=0.17)。1年时,正常组48例中有6例出现吞咽困难,动力障碍组33例中有5例(P=0.9)。

结论

术前对食管动力进行测压评估与术后结果无关,食管动力障碍不应被视为腹腔镜nissen胃底折叠术的禁忌证。

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