van Beek E J, Büller H R, van Royen E A, van Everdingen J J, ten Cate J W
Afd. Hematologie, Academisch Medisch Centrum, Amsterdam.
Ned Tijdschr Geneeskd. 1992 Feb 15;136(7):319-23.
To gain insight into the incidence of suspected pulmonary embolism in the Netherlands and to evaluate the diagnostic strategy and therapeutic consequences in this patient population, a questionnaire was sent to all practising medical and pulmonary specialists (members of the respective associations). The number of patients admitted with suspected pulmonary embolism in the previous month and the diagnostic and therapeutic management in the last patient were requested. A reply was received from 698 internists and 272 pulmonologists (total response 73%). The management by the two specialist groups was not different. In the previous month 970 respondents treated 2245 patients for suspected pulmonary embolism. Extrapolated this means that 2.6 patients per 1000 inhabitants in the Netherlands are suspected of pulmonary embolism each year. Of the respondents, 95% had facilities to obtain a perfusion-ventilation scan. Of this group, 97% performed a perfusion scan when pulmonary embolism was suspected. A normal scan was found in 16% of the patients. A ventilation scan was performed in 71% of the patients with an abnormal perfusion scan result. Of all patients with an abnormal perfusion scan, 87% were treated with anticoagulants. The ventilation scan had little influence on this decision. The clinical suspicion of pulmonary embolism is a frequent clinical problem. The fact that of all patients with an abnormal perfusion scan 87% are treated, indicates overtreatment. The diagnosis of pulmonary embolism needs to be improved.
为深入了解荷兰疑似肺栓塞的发病率,并评估该患者群体的诊断策略及治疗结果,向所有执业医学专家和肺科专家(各协会成员)发送了一份调查问卷。问卷询问了前一个月收治的疑似肺栓塞患者数量以及最后一位患者的诊断和治疗情况。收到了698名内科医生和272名肺科医生的回复(总回复率73%)。两个专家小组的治疗方式没有差异。在前一个月,970名受访者为2245名疑似肺栓塞患者进行了治疗。由此推断,荷兰每年每1000名居民中有2.6人疑似患有肺栓塞。在受访者中,95%具备进行灌注-通气扫描的设备。在这一组中,97%在怀疑肺栓塞时进行了灌注扫描。16%的患者扫描结果正常。71%灌注扫描结果异常的患者进行了通气扫描。在所有灌注扫描结果异常的患者中,87%接受了抗凝治疗。通气扫描对这一治疗决策影响不大。临床怀疑肺栓塞是一个常见的临床问题。所有灌注扫描结果异常的患者中有87%接受治疗,这表明存在过度治疗的情况。肺栓塞的诊断需要改进。