Gur Ali, Sarac Aysegul Jale, Cevik Remzi, Altindag Ozlem, Sarac Serdar
Physical Medicine and Rehabilitation, School of Medicine, Dicle University, Diyarbakir, Turkey.
Lasers Surg Med. 2004;35(3):229-35. doi: 10.1002/lsm.20082.
A prospective, double-blind, randomized, and controlled trial was conducted in patients with chronic myofascial pain syndrome (MPS) in the neck to evaluate the effects of infrared low level 904 nm Gallium-Arsenide (Ga-As) laser therapy (LLLT) on clinical and quality of life (QoL).
STUDY DESIGN/PATIENTS AND METHODS: The study group consisted of 60 MPS patients. Patients were randomly assigned to two treatment groups: Group I (actual laser; 30 patients) and Group II (placebo laser; 30 patients). LLLT continued daily for 2 weeks except weekends. Follow-up measures were evaluated at baseline, 2, 3, and 12 weeks. All patients were evaluated with respect to pain at rest, pain at movement, number of trigger points (TP), the Neck Pain and Disability Visual Analog Scale (NPAD), Beck depression Inventory (BDI), and the Nottingham Health Profile (NHP).
In active laser group, statistically significant improvements were detected in all outcome measures compared with baseline (P < 0.01) while in the placebo laser group, significant improvements were detected in only pain score at rest at the 1 week later of the end of treatment. The score for self-assessed improvement of pain was significantly different between the active and placebo laser groups (63 vs. 19%) (P < 0.01).
This study revealed that short-period application of LLLT is effective in pain relief and in the improvement of functional ability and QoL in patients with MPS.
对颈部慢性肌筋膜疼痛综合征(MPS)患者进行了一项前瞻性、双盲、随机对照试验,以评估904纳米红外低强度砷化镓(Ga-As)激光疗法(LLLT)对临床症状及生活质量(QoL)的影响。
研究设计/患者与方法:研究组由60例MPS患者组成。患者被随机分为两个治疗组:第一组(实际激光治疗组;30例患者)和第二组(安慰剂激光治疗组;30例患者)。除周末外,LLLT每天持续进行2周。在基线、第2、3和12周进行随访评估。对所有患者进行静息痛、运动痛、触发点(TP)数量、颈部疼痛与功能障碍视觉模拟量表(NPAD)、贝克抑郁量表(BDI)以及诺丁汉健康量表(NHP)的评估。
与基线相比,活性激光治疗组在所有结局指标上均有统计学意义的改善(P < 0.01),而安慰剂激光治疗组仅在治疗结束后1周的静息痛评分上有显著改善。活性激光治疗组与安慰剂激光治疗组之间疼痛自我评估改善得分有显著差异(63%对19%)(P < 0.01)。
本研究表明,短期应用LLLT对缓解MPS患者的疼痛、改善功能能力及生活质量有效。