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接触二氯甲烷及其燃烧产物光气后出现的肺部毒性。

Pulmonary toxicity following exposure to methylene chloride and its combustion product, phosgene.

作者信息

Snyder R W, Mishel H S, Christensen G C

机构信息

Department of Internal Medicine, Abington Memorial Hospital, Pa.

出版信息

Chest. 1992 Mar;101(3):860-1. doi: 10.1378/chest.101.3.860.

DOI:10.1378/chest.101.3.860
PMID:1541163
Abstract

Chemical paint removers containing methylene chloride are widely used in domestic and industrial settings where exposure to a heat source with conversion to phosgene is possible. We describe a case of noncardiogenic pulmonary edema and subsequent hyperreactive airways following such an exposure. In addition, the various problems that have been associated with exposure to methylene chloride and phosgene are reviewed.

摘要

含有二氯甲烷的化学脱漆剂广泛应用于家庭和工业环境中,在这些环境中有可能因接触热源而转化为光气。我们描述了一例在接触此类物质后发生的非心源性肺水肿及随后的气道高反应性病例。此外,还综述了与接触二氯甲烷和光气相关的各种问题。

相似文献

1
Pulmonary toxicity following exposure to methylene chloride and its combustion product, phosgene.接触二氯甲烷及其燃烧产物光气后出现的肺部毒性。
Chest. 1992 Mar;101(3):860-1. doi: 10.1378/chest.101.3.860.
2
Pulmonary toxicity following exposure to methylene chloride and its combustion product, phosgene.接触二氯甲烷及其燃烧产物光气后出现的肺毒性。
Chest. 1992 Dec;102(6):1921. doi: 10.1378/chest.102.6.1921-b.
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Diffuse pulmonary injury following paint remover exposure.接触脱漆剂后发生的弥漫性肺损伤。
Am J Med. 1986 Oct;81(4):702-4. doi: 10.1016/0002-9343(86)90560-7.
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[Radiological observation on pulmonary edema due to phosgene poisoning].
Zhonghua Fang She Xue Za Zhi. 1984 Aug;18(3):171-3.
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[Clinical and radiological studies on 15 cases of acute phosgene poisoning].
Zhonghua Jie He He Hu Xi Za Zhi. 1992 Aug;15(4):231-2, 256.
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Phosgene exposure: mechanisms of injury and treatment strategies.
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[Clinical course and pathology of phosgene poisoning (author's transl)].光气中毒的临床病程与病理学(作者译)
Pneumonologie. 1974;150(2-4):139-48. doi: 10.1007/BF02179311.
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Phosgene poisoning caused by the use of chemical paint removers containing methylene chloride in ill-ventilated rooms heated by kerosene stoves.在使用煤油炉取暖且通风不良的房间里,因使用含有二氯甲烷的化学脱漆剂而导致光气中毒。
Br J Ind Med. 1960 Jul;17(3):187-9. doi: 10.1136/oem.17.3.187.
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[Early diagnosis by x-rays of toxic pulmonary edema in dogs].[犬中毒性肺水肿的X线早期诊断]
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Pulmonary edema of environmental origin.
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引用本文的文献

1
Case Report: Sudden death caused by methylene chloride poisoning.病例报告:二氯甲烷中毒导致的猝死。
Front Pharmacol. 2024 Nov 26;15:1471744. doi: 10.3389/fphar.2024.1471744. eCollection 2024.
2
Methylene chloride poisoning in a cabinet worker.一名橱柜工人的二氯甲烷中毒事件。
Environ Health Perspect. 1999 Sep;107(9):769-72. doi: 10.1289/ehp.99107769.
3
Acute lung injury after phosgene inhalation.光气吸入后急性肺损伤
Korean J Intern Med. 1996 Jan;11(1):87-92. doi: 10.3904/kjim.1996.11.1.87.
4
Phosgene effects on F-actin organization and concentration in cells cultured from sheep and rat lung.光气对绵羊和大鼠肺细胞中F-肌动蛋白组织和浓度的影响。
Cell Biol Toxicol. 1994 Feb;10(1):45-58. doi: 10.1007/BF00757186.