A novel probe for human DNA fingerprinting based on chi-like sequences.
作者信息
Ehtesham N Z, Das A, Hasnain S E
机构信息
National Institute of Immunology, New Delhi, India.
出版信息
Gene. 1992 Feb 15;111(2):261-3. doi: 10.1016/0378-1119(92)90697-n.
PMID:1541404
Abstract
A synthetic oligodeoxyribonucleotide (oligo) containing crossover initiating hotspot-like sequences was designed on the assumption that hypervariability is partly due to the presence of molecular signals which promote recombination. This oligo, when used as a probe for human DNA fingerprinting, generated individual-specific DNA band patterns. The probability of two unrelated individuals having the same DNA band pattern, using this probe, was estimated to be 1.9 x 10(-13).
摘要
Zotero 插件