BLACK-SCHAFFER B, MILAM J W, BROCKMAN D D, COONRAD E V, SILVERMAN S B
J Exp Med. 1950 May 1;91(5):539-48. doi: 10.1084/jem.91.5.539.
In the hypersensitive animal a single inoculation of homologous antigen mixed with Shwartzman preparatory toxin may lead to the production of a Shwartzman reaction which functions as an amplifier of the antigen-antibody tissue response. The combination of antigen and bacterial toxin does not alter the antigenicity of purified bovine gamma globulin. This form of the Shwartzman phenomenon may be useful in the investigation of hyperergic tissue reactions.
在过敏动物中,将同源抗原与施瓦茨曼预毒素混合进行单次接种,可能会引发施瓦茨曼反应,该反应可作为抗原 - 抗体组织反应的放大器。抗原与细菌毒素的结合不会改变纯化牛γ球蛋白的抗原性。这种形式的施瓦茨曼现象可能有助于研究过敏组织反应。