COHEN S S, ARBOGAST R
J Exp Med. 1950 Jun 1;91(6):619-36. doi: 10.1084/jem.91.6.619.
Various chemical and physiological aspects of the reproductive cycles of r(+) and r strains of T2, T4, and T6 viruses have been examined and compared. These include the ultraviolet absorption spectra in which differences between r and r(+) strains were not observed, though they were obtained in the case of T2, T4, and T6. Adsorption of T4 and T6 was found to require the adsorption cofactor l-tryptophane. Among the r and r(+) strains of these viruses limiting tryptophane requirements for adsorption were found to be different. Some differences were observed in the one-step growth curves of these viruses under conditions of single and multiple infection. The turbidity-time relations of infected cultures were characteristically different. The rates of DNA and protein synthesis in the infected cells were found to be independent of the viruses used. Certain implications of the data have been discussed.
对T2、T4和T6病毒的r(+)和r株系繁殖周期的各种化学和生理学方面进行了研究和比较。这些方面包括紫外线吸收光谱,在T2、T4和T6的情况下虽能获得该光谱,但未观察到r和r(+)株系之间存在差异。发现T4和T6的吸附需要吸附辅因子L-色氨酸。在这些病毒的r和r(+)株系中,发现吸附所需的色氨酸限制量有所不同。在单重感染和多重感染条件下,观察到这些病毒的一步生长曲线存在一些差异。受感染培养物的浊度-时间关系具有明显差异。发现受感染细胞中DNA和蛋白质的合成速率与所使用的病毒无关。已对这些数据的某些含义进行了讨论。