Ngan M, Chien K, Lee S
Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, California.
Mod Pathol. 1992 Jan;5(1):68-70.
A total of 146 patients with newly diagnosed acute lymphoblastic leukemia (ALL) occurring over a 9 1/2-yr period were reviewed; four of these patients (2.7%) had blast cells that stained positively with Sudan Black B. These four, two adults and two children, were all B type. Electron microscopy was performed on three of these four cases and showed the sudanophilia to be due to lipid droplets. The lipid droplets were also demonstrated in one of the three cases by Oil Red O stain. Therefore, Sudan Black B used alone to differentiate lymphoid from myeloid leukemia may be misleading.
回顾了在9年半时间里新诊断的146例急性淋巴细胞白血病（ALL）患者；其中4例患者（2.7%）的原始细胞苏丹黑B染色呈阳性。这4例患者，2名成人和2名儿童，均为B型。对这4例中的3例进行了电子显微镜检查，结果显示嗜苏丹现象是由脂滴引起的。在这3例中的1例中，油红O染色也证实了脂滴的存在。因此，单独使用苏丹黑B来区分淋巴细胞白血病和髓细胞白血病可能会产生误导。
