Klujber V, Koós R, Schuler D, Bocsi J
Semmelweis Orvostudományi Egyetem Budapest, II. Gyermekklinika.
Orv Hetil. 1996 May 26;137(21):1139-42.
The authors used a cell-surface-marker analysis by flow cytometry for immunophenotyping of pediatric leukemia from 1993. Results of their first one-hundred cases were summarized. They examined 68 bone-marrow samples from 58 patients affected by leukemia, and diagnosed 19 acute myeloid leukemia (32%), 5 T-cell acute lymphoid leukemia (8%), 32 B-cell acute lymphoid leukemia (54%) and 2 biphenotypic leukemia (5%). A higher CD34 antigen positivity was found compared to adults. They analysed the incidence and prognostic significance of myeloid + lymphoid leukemia and lymphoid + myeloid leukemia cases. Nondiagnostic and unsuccessful cases were got according to the literature.
自1993年起，作者采用流式细胞术进行细胞表面标志物分析，以对小儿白血病进行免疫分型。他们总结了最初100例病例的结果。他们检查了58例白血病患者的68份骨髓样本，诊断出19例急性髓系白血病（32%）、5例T细胞急性淋巴细胞白血病（8%）、32例B细胞急性淋巴细胞白血病（54%）和2例双表型白血病（5%）。与成人相比，发现CD34抗原阳性率更高。他们分析了髓系+淋巴系白血病和淋巴系+髓系白血病病例的发生率及预后意义。根据文献得出了非诊断性和未成功的病例。
