鬼臼毒素、秋水仙碱、乌拉坦和氮芥对正常及肾上腺切除大鼠淋巴组织呼吸的影响。
The effect of podophyllotoxin, colchicine, urethane, and nitrogen mustard on the respiration of normal and suprarenalectomized rat lymphatic tissue.
作者信息
MILLER Z B, DAVISON C, SMITH P K
出版信息
J Exp Med. 1950 Aug;92(2):113-9. doi: 10.1084/jem.92.2.113.
Abstract
The injection of podophyllotoxin, colchicine, and a nitrogen mustard derivative, methyl-bis(beta-chloroethyl)amine, into normal animals causes a reduction of the respiration of the lymphatic tissues, spleen, and/or thymus. No effect was demonstrable on kidney, a representative tissue of non-lymphatic origin. The degree of inhibition was considerably less in suprarenalectomized animals, suggesting that the inhibition is mediated by the suprarenal gland.
摘要
向正常动物注射鬼臼毒素、秋水仙碱和一种氮芥衍生物——甲基双（β-氯乙基）胺，会导致淋巴组织、脾脏和/或胸腺的呼吸作用减弱。对肾脏（非淋巴起源的代表性组织）未显示出任何影响。在肾上腺切除的动物中，抑制程度明显较低，这表明这种抑制作用是由肾上腺介导的。
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