Godaux E, Koulischer D, Jacquy J
Department of Neurophysiology, Faculty of Medicine, University of Mons, Belgium.
Ann Neurol. 1992 Jan;31(1):93-100. doi: 10.1002/ana.410310117.
Parkinsonian bradykinesia is defined by a slowness in the execution of movement. We studied the pathophysiology of this symptom in rapid arm-reaching movements to a visual target carried out in a reaction-time task. The major cause of bradykinesia was found to be depression in the rate of rise of electromyographic activity. The amplitude of the peak of this activity did not change significantly. There was no change either in the sequential activation of muscles, in the amount of co-contraction activity, in the accuracy of aim toward the visual target, or in the movement trajectory.
帕金森病性运动迟缓的定义是运动执行缓慢。我们在一项反应时任务中，针对快速伸手够向视觉目标的动作，研究了该症状的病理生理学。结果发现，运动迟缓的主要原因是肌电图活动上升速率降低。该活动峰值的幅度没有显著变化。肌肉的顺序激活、共同收缩活动量、朝向视觉目标的瞄准准确性或运动轨迹也均未改变。
