Taylor R G, Abresch R T, Lieberman J S, Fowler W M, Entrikin R K
Department of Physical Medicine and Rehabilitation, UC Davis 95616.
Arch Phys Med Rehabil. 1992 Mar;73(3):228-32.
This report describes and assesses a technique to indirectly stimulate and quantify the human in vivo muscle response for clinical use. A method has been developed to isolate, stimulate, and record the flexor function of the first dorsal interosseus and first volar interosseus at the metacarpophalangeal (MCP) joint by stimulation of the ulnar nerve at the wrist. A microprocessor-based data acquisition and analysis system was built to deliver the electric stimulus and convert the muscle action potential (M-wave) and force measurements into digital form for analysis. To evaluate the technique, the twitch, paired twitch, and tetanic contractions were analyzed in 81 normal subjects. The tension developed by the youngest subjects (14 to 19 years old) was significantly less than the tension developed by subjects in the three older groups (20 to 34 years, 35 to 50 years, and 50 to 65 years); the tensions in the older groups were not significantly different from each other. Only minor gender differences were noted. This indicates that it is necessary to use age-group controls when looking for evidence of a muscle contractile abnormality in patients with neuromuscular disorders. posttetanic potentiation of the twitch was observed in all healthy subjects, and there was no evidence of an age or gender influence. The posttetanic increase in twitch tension was not associated with a prolongation of the twitch contraction time.
本报告描述并评估了一种用于临床的间接刺激和量化人体体内肌肉反应的技术。已开发出一种方法，通过刺激腕部的尺神经来分离、刺激并记录第一掌背侧骨间肌和第一掌掌侧骨间肌在掌指（MCP）关节处的屈肌功能。构建了一个基于微处理器的数据采集和分析系统，以提供电刺激，并将肌肉动作电位（M波）和力量测量值转换为数字形式进行分析。为评估该技术，对81名正常受试者的单收缩、双脉冲刺激收缩和强直收缩进行了分析。最年轻受试者（14至19岁）产生的张力明显低于其他三个年龄组（20至34岁、35至50岁和50至65岁）的受试者产生的张力；年龄较大组之间的张力无显著差异。仅观察到轻微的性别差异。这表明，在寻找神经肌肉疾病患者肌肉收缩异常的证据时，有必要使用年龄组对照。在所有健康受试者中均观察到单收缩的强直后增强，且没有年龄或性别影响的证据。强直后单收缩张力的增加与单收缩收缩时间的延长无关。
