Gekht B M, Sanadze A G, Strokov I A
Biull Eksp Biol Med. 1984 Jul;98(7):28-31.
Muscle contractility of the thumb was studied in 24 normal subjects, 84 patients with myasthenia and 4 patients with hypothyrosis in response to supramaximal stimulation, on the basis of the time of contraction and semi-relaxation, staircase phenomena, and posttetanic potentiation. During hormonal therapy, the patients with myasthenia and those with hypothyrosis treated by substitution therapy manifested the normalization of the staircase and posttetanic potentiation, reduction of the contraction force and twitch time during single contraction. The comparison of the changes seen in the contraction force, staircase and posttetanic potentiation during examination of the patients over time suggested that the muscle has a regulatory system that determines the force and twitch time of muscle contraction.
基于收缩和半松弛时间、阶梯现象以及强直后增强，对24名正常受试者、84名重症肌无力患者和4名甲状腺功能减退患者的拇指肌肉收缩性进行了研究，观察其对超强刺激的反应。在激素治疗期间，接受替代治疗的重症肌无力患者和甲状腺功能减退患者表现出阶梯现象和强直后增强正常化，单次收缩时收缩力和抽搐时间缩短。随着时间推移对患者检查期间收缩力、阶梯现象和强直后增强变化的比较表明，肌肉具有一个调节系统，该系统决定肌肉收缩的力量和抽搐时间。
