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淀粉样蛋白与淀粉样变性

Amyloid and amyloidosis.

作者信息

Cohen A S, Jones L A

机构信息

Boston City Hospital, Boston University School of Medicine, Massachusetts.

出版信息

Curr Opin Rheumatol. 1992 Feb;4(1):94-105.

PMID:1543671
Abstract

Discovery of the different proteins that constitute the multiple types of amyloid has led to an increasing variety of studies in the literature of diverse medical subspecialties. In fact, in this review, the editors have chosen to review the beta 2-microglobulin amyloid of long-term hemodialysis in the section on renal disease. The current review focuses on the rapidly advancing basic studies of familial, amyloid A protein amyloid and the relevant clinical studies, although the research on amyloid light-chain protein and other forms of amyloidosis is also noted.

摘要

构成多种类型淀粉样蛋白的不同蛋白质的发现,促使文献中不同医学亚专业的研究日益增多。事实上,在本综述中,编辑们选择在肾脏疾病章节中回顾长期血液透析患者的β2微球蛋白淀粉样变。尽管也提到了关于淀粉样轻链蛋白和其他形式淀粉样变性的研究,但当前综述重点关注家族性淀粉样A蛋白淀粉样变快速发展的基础研究及相关临床研究。

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